000			03112cam a22003254a 4500
001			13781128
008			041109s2005 njua b 001 0 eng
020			_a1588293831 (alk. paper)
040			_cIHBT
082	0	0	_a615.19 NAT
100			_aZhang, Lixin [ed.]
245	0	0	_aNatural products : _bdrug discovery and therapeutic medicine / _cedited by Lixin Zhang, Arnold L. Demain.
260			_aTotowa, N.J. : _bHumana Press, _cc2005.
300			_axiv, 382 p. : _bill. ; _c26 cm.
504			_aIncludes bibliographical references and index.
505	0		_aNatural products and drug discovery / Arnold L. Demain and Lixin Zhang -- Integrated approaches for discovering novel drugs from microbial natural products / Lixin Zhang -- Automated analyses of HPLC profiles of microbial extracts: a new tool for drug discovery screening / Jose R. Tormo and Juan B. Garcia -- Manipulating microbial metabolites for drug discovery and production / C. Richard Hutchinson -- Improving drug discovery from microorganisms / Chris M. Farnet and Emmanuel Zazopoulos -- Developments in strain improvement technology: evolutionary engineering of industrial microorganisms through gene, pathway, and genome shuffling / Stephen B. del Cardayr -- The discovery of anticancer drugs from natural sources / David J. Newman and Gordon M. Cragg -- Case studies in natural product optimization: novel antitumor agents derived from taxus brevifolia and catharanthus roseus / Jian Hong and Shu-Hui Chen --
505	0		_aTerpenoids as therapeutic drugs and pharmaceutical agents / Guangyi Wang, Weiping Tang and Robert R. Bidigare -- Challenges and opportunities in the Chinese herbal drug industry / Wei Jia and Lixin Zhang -- Arsenic trioxide and leukemia: from bedside to bench / Guo-Qiang Chen ... [et al.] -- New methods to access microbial diversity for small molecule discovery / Karsten Zengler, Ashish Paradkar, and Martin Keller -- Accessing the genomes of uncultivated microbes for novel natural products / Asuncion Martinez ... [et al.] -- New natural product diversity from marine actinomycetes / Paul R. Jensen and William Fenical -- Novel natural products from rainforest endophytes / Gary Strobel, Bryn Daisy, and Uvidelio Castillo -- Biological, economic, ecological, and legal aspects of harvesting traditional medicine in Ecuador / Alexandra Guevara-Aguirre and Ximena Chiriboga.
600			_aDemain, Arnold L.
650		0	_aPharmacognosy. _94342
650	1	2	_aDrug Design. _95441
650	1	2	_aPharmacognosy. _94342
650	2	2	_aBiological Factors _xtherapeutic use.
650	2	2	_aBiological Products _xtherapeutic use.
650	2	2	_aPharmacogenetics.
700	1		_aZhang, Lixin, _cPh. D.
700	1		_aDemain, A. L. _q(Arnold L.), _d1927-
856	4	1	_3Table of contents _uhttp://www.loc.gov/catdir/toc/ecip053/2004026635.html _yhttp://14.139.59.218:80/cgi-bin/koha/opac-detail.pl?biblionumber=Ubiblionumber
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0825/2004026635-d.html _yhttp://14.139.59.218:80/cgi-bin/koha/opac-detail.pl?biblionumber=Ubiblionumber
942			_2ddc _cBK
999			_c8103 _d8103