For the Love of Enzymes: The Odyssey of a Biochemist (Record no. 4943)

000 -LEADER
fixed length control field 03022nam a2200217Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field 00IHBT
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140908102152.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130910s9999 xx 000 0 und d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 0674307763
040 ## - CATALOGING SOURCE
Transcribing agency IHBT
041 ## - LANGUAGE CODE
Language code of original ENG
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572.7
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Kornberg, Arthur
Dates associated with a name 1918-2007
9 (RLIN) 8684
245 ## - TITLE STATEMENT
Title For the Love of Enzymes: The Odyssey of a Biochemist
Statement of responsibility, etc. Arthur Kornberg
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. England
Name of publisher, distributor, etc. Harbour University Press
Date of publication, distribution, etc. 1989
300 ## - PHYSICAL DESCRIPTION
Extent xvi, 336p.
500 ## - GENERAL NOTE
General note In 1645 the Japanese samurai Musashi Miamoto wrote A Book of Five Rings, which described the attitudes necessary for individual success. Though he was a swordsman, his book was not limited to combat but addressed the much broader question of how to achieve excellence in life through study, discipline, and planning. It is still avidly read in Japan today.

Arthur Kornberg's book is a modern-day Book of Five Rings that replaces the medium of swordsmanship with that of biochemistry, particularly enzymology. As Kornberg describes his successive research problems, the challenges they presented, and the ultimate accomplishments that resulted, he provides us with a primer in the strategies needed to do scientific work of great significance. Moreover, these strategies are played out in the context of solving some of the great biochemical problems of the twentieth century.

The ability to manipulate and alter DNA fired a revolution that forever changed the nature of biology. Arthur Kornberg is a primary architect of that revolution, arguably one of the two or three most important biologists of this time. Prior to Kornberg, genetic information and later DNA were imbued by biologists with an almost vitalistic aura. Kornberg demonstrated that DNA is a molecule synthesized by enzymes, like all other chemical constituents of the cell. More important, he trained a school of scientists who focused on and discovered many of the enzymatic activities that act on DNA. It is these enzymes in particular that allow modern "genetic engineering."

For the Love of Enzymes does not describe a single lucky or hard-won accomplishment. Rather, it is the story of thirty years of decisive campaigns, nearly all of which led to insights of major significance. In relating his story, Kornberg never avoids the difficult question of "why": why he felt classical nutritional studies had reached a plateau, why he turned to enzymology as a discipline in which the important answers would be found, and why he believes the study of enzymes will grow ever more important as we face the new scientific frontier of brain function.

This book will challenge students of biology and chemistry at all levels who want to do important work rather than simply follow popular trends. It will also delight and inform readers who wish to understand how "real" science is done, and to learn of the values that guide one of our greatest researchers.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemists--United States--Biography
9 (RLIN) 8685
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Enzymes
9 (RLIN) 2005
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://14.139.59.218:80/cgi-bin/koha/opac-detail.pl?biblionumber=4943
Link text http://14.139.59.218:80/cgi-bin/koha/opac-detail.pl?biblionumber=4943
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type BOOK
Source of classification or shelving scheme
Holdings
Source of acquisition Price effective from Permanent Location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Barcode Damaged status Lost status Cost, normal purchase price Withdrawn status Current Location Full call number
Researchco Book Center, New Delhi, Bill No. 179, Dated 11-03-20102013-12-18CSIR-Institute of Himalayan Bioresource Technology 2013-12-18 2013-12-18 BOOKS4968  1092.00 CSIR-Institute of Himalayan Bioresource Technology 572.7 FOR





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