Drug Metabolism in Drug Design and Development : Basic Concepts and Practice (Record no. 4850)

000 -LEADER
fixed length control field 02590nam a2200325Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field 00IHBT
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140908102151.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130910s9999 xx 000 0 und d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780471733133
040 ## - CATALOGING SOURCE
Transcribing agency IHBT
041 ## - LANGUAGE CODE
Language code of original ENG
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615.1
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Zhang, Donglu [Ed.]
9 (RLIN) 7128
245 ## - TITLE STATEMENT
Title Drug Metabolism in Drug Design and Development : Basic Concepts and Practice
Statement of responsibility, etc. Edited by Donglu Zhang, Mingshe Zhu, W. Griffith Humphreys
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Canada
Name of publisher, distributor, etc. John-Wiley
Date of publication, distribution, etc. 2008
300 ## - PHYSICAL DESCRIPTION
Extent xix, 609p.
500 ## - GENERAL NOTE
General note The essentials of drug metabolism vital to developing new therapeutic entities

Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge of sophisticated analytical technologies and expertise in mechanistic and kinetic enzymology, organic reaction mechanism, pharmacokinetic analysis, animal physiology, basic chemical toxicology, preclinical pharmacology, and molecular biology. With chapters contributed by experts in their specific areas, this reference covers:

Basic concepts of drug metabolism

The role of drug metabolism in the pharmaceutical industry

Analytical techniques in drug metabolism

Common experimental approaches and protocols

Drug Metabolism in Drug Design and Development emphasizes practical considerations such as the data needed, the experiments and analytical methods typically employed, and the interpretation and application of data. Chapters highlight facts, common protocols, detailed experimental designs, applications, and limitations of techniques.

This is a comprehensive, hands-on reference for drug metabolism researchers as well as other professionals involved in pre-clinical drug discovery and development.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drugs Metabolism
9 (RLIN) 7129
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drugs Design
9 (RLIN) 7130
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drug Evaluation methods
9 (RLIN) 7131
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drug Design
9 (RLIN) 5441
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmaceutical Preparations
9 (RLIN) 7132
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drug development
9 (RLIN) 4359
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Zhu, Mingshe [Ed.]
9 (RLIN) 7133
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Humphreys, W. Griffith. [Ed.]
9 (RLIN) 7134
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://www.loc.gov/catdir/toc/ecip0717/2007017661.html
Link text Table of contents only
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://www.loc.gov/catdir/enhancements/fy0739/2007017661-d.html
Link text Publisher description
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://www.loc.gov/catdir/enhancements/fy0805/2007017661-b.html
Link text Contributor biographical information
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://14.139.59.218:80/cgi-bin/koha/opac-detail.pl?biblionumber=4850
Link text http://14.139.59.218:80/cgi-bin/koha/opac-detail.pl?biblionumber=4850
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type BOOK
Source of classification or shelving scheme
Holdings
Source of acquisition Price effective from Permanent Location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Barcode Damaged status Lost status Cost, normal purchase price Withdrawn status Current Location Full call number
Prashant Book Agency, New Delhi, Bill No.301, Dated 25-09-092013-12-18CSIR-Institute of Himalayan Bioresource Technology 2013-12-18 2013-12-18 BOOKS4854  5397.75 CSIR-Institute of Himalayan Bioresource Technology 615.1 DRU





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